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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Fluorides
drug:
Sodium Chloride
Research Papers that Mention the Interaction
“The results clearly confirm the remineralization-promoting effect of the fluoride added to the dental salt.”
[Influence on de- and remineralization of dental enamel by toothbrushing with a dental salt].“ Sodium chloride inhibition was enhanced to 34-54% under conditions of enzyme stimulation by guanine nucleotides (GTP and its nonhydrolyzable analog 5'-guanylyl imidodiphosphate), fluoride anion , and agonists (ovine luteinizing hormone (oLH) and the beta-adrenergic catecholamine isoproterenol) acting at stimulatory receptors linked to adenylate cyclase.”
Inhibition of adenylate cyclase from luteinized rat ovary by monovalent cations: roles of the stimulatory guanine nucleotide-binding regulatory component and stimulatory hormone receptor.“Maximal binding occurred in the presence of 200 mM NaCl : potassium, lithium, rubidium and calcium substituted poorly for sodium; and bromide, fluoride , iodide, sulfate and phosphate were less effective anions than chloride.”
“These data indicate that the fluoride ion dissipates the concentration gradient in the renal medulla largely by inhibiting NaCl reabsorption in the ascending limb of Henle's loop and inhibits antidiuretic hormone-mediated water reabsorption across the collecting duct.”
“The removal efficiencies of F- and Cl- both decreased with increasing feed concentration of coexisting NaCl.”
Effective fluoride removal from brackish groundwaters by flow-electrode capacitive deionization (FCDI) under a continuous-flow mode.“There was a slight variation in the amount of fluoride taken up with storage temperature and with the presence of sodium chloride.”
“This change in inhibition pattern was attributed to a change in ionic strength or perhaps pH of the solution since fluoride ion was also found to become a competitive inhibitor of AAP at pH 8.0 in the presence of 2 M NaCl.”
“These studies show that the presence of fluoride decreases the amount of bone salt dissolved over a short time interval but they do not indicate whether this decrease is due to a change in the solubility equilibrium state or to the rate at which equilibrium is approached.”
“… fluoride … bone salt consists of many reports which show, principally, that (a) a smaller amout of enamel, or of hydroxyapatite, is dissolved in fluoride-containing solutions … who have lived in areas in which the water was treated with fluoride than if the water was not treated with fluoride (11).”
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