“In addition, the combination of oleic acid with fluoride altered the bacterial biovolume of the biofilms without bactericidal activity.”
“The combination of oleic acid with fluoride inhibited EPS formation more strongly than did fluoride or oleic acid alone.”
“This study investigated whether oleic acid , a monounsaturated fatty acid, can enhance the effect of fluoride on extracellular polysaccharide (EPS) formation by Streptococcus mutans UA159 biofilms at sub-minimum inhibitory concentration levels, via microbiological and biochemical methods, confocal fluorescence microscopy, and real-time PCR.”