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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Fluorides
drug:
Nifedipine
Research Papers that Mention the Interaction
“In contrast, low fluoride, high fluoride with nifedipine, and low fluoride with nifedipine reduced the Cav1.2 expression level.”
Effect of fluoride exposure on mRNA expression of cav1.2 and calcium signal pathway apoptosis regulators in PC12 cells.“However, the levels of [Ca2+]i, Cav1.2, c-fos, c-jun, Runx2, and OSX induced by fluoride were significantly altered and even reversed in the presence of nifedipine.”
“Lysosomal enzyme release by exocytosis in rabbit polymorphonuclear leukocytes, induced by chemotactic peptide ionophore A 23187 or fluoride , is inhibited by high concentrations (0.2-1 mmol/l) of the calcium antagonists verapamil and nifedipine.”
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