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Discover Supplement-Drug Interactions

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Last Updated: 2 months ago

Possible Interaction: Fluorides and NAD





Research Papers that Mention the Interaction

Exposure of red cells to fluoride produces a variety of metabolic alterations, most of which are based upon the secondary effects of enolase inhibition, which reduces pyruvate synthesis and interferes with the regeneration of diphosphopyridine nucleotide ( NAD).
The Journal of clinical investigation  •  1971  |  View Paper
Nicotinamide adenine dinucleotide (NAD) apparently increased the degree of pyruvate reversal when fluoride , but not iodoacetate, was the inhibitory agent.
Journal of bacteriology  •  1963  |  View Paper
Fluoride competitively inhibits the catalytic activity of the enzyme and appears in a ternary enzyme-reduced nicotinamide adenine dinucleotide (NADH)-fluoride complex detectable in fluorescence and circular dichroism measurements.
Biochemistry  •  1981  |  View Paper