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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Fluorides and Isoniazid

supplement:

Fluorides

Research Papers that Mention the Interaction

Administration of isoniazid in human patients may increase the metabolism of enflurane and increase serum fluoride ion concentrations (1) to levels that may transiently impair renal function (2,3).
Anesthesia and analgesia  •  1989  |  View Paper
Following anaesthesia with enflurane, some patients receiving isoniazid have increased serum concentrations of fluoride ion , presumably because of induction of an isozyme of cytochrome P450 which is responsible for enflurane biodegradation.
British journal of anaesthesia  •  1989  |  View Paper