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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
supplement:
Fluorides
drug:
Isoflurophate
Research Papers that Mention the Interaction
“… DFP, … fluoride ion (by-product of the initial phosphorylation reaction) to induce a unique modulation in the optical properties of the sensing system which leads to …, acids, and anions were unable to induce similar optical modulation due to lack of both electrophilic phosphorus and fluorine in the same molecule.”
A dual-channel optical chemical sensing system for selective detection of nerve agent simulant DFP“The product fluoride effectively inhibited OPH-catalyzed hydrolysis of DFP by a linear mixed inhibition (inhibition constant Ki ~ 3.21 mM), which was partially released by TEA adding at initial or later reaction stage.”
“In the presence of DFP , the electrode potential decreases rapidly with time due to the catalyzed hydrolysis of DFP and the production of fluoride ion.”
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