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“Pretreatment of CM with serine proteinase inhibitors 4-(2-aminoethyl)benzenesulfonyl fluoride and diisopropyl fluorophosphate completely inhibited Abeta degradation.”
The Journal of Biological Chemistry • 1999 | View Paper
“The product fluoride effectively inhibited OPH-catalyzed hydrolysis of DFP by a linear mixed inhibition (inhibition constant Ki ~ 3.21 mM), which was partially released by TEA adding at initial or later reaction stage.”
“In the presence of DFP , the electrode potential decreases rapidly with time due to the catalyzed hydrolysis of DFP and the production of fluoride ion.”