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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Fluorides and Insulin

supplement:

Fluorides

drug:

Insulin

Research Papers that Mention the Interaction

I discuss how NIS expression and activity is inhibited by thyroglobulin (Tg), tumour necrosis factor alpha (TNF-α), … 1 (TGF-β1), interleukin 6 (IL-6) and Interleukin 1 beta (IL-1β), interferon-γ (IFN-γ), insulin like growth factor 1 (IGF-…-kinase (PI3K) and how fluoride upregulates expression … biomarkers.
International journal of environmental research and public health  •  2019  |  View Paper
Fluoride and zinc also inhibited glucan production, especially insoluble glucan, in fed-batch biofilms.
FEMS microbiology letters  •  2006  |  View Paper
This observation coincides with experiments published elsewhere indicating that fluoride intake at concentrations 5 microM or greater, inhibits the secretion of insulin.
Medicina  •  1997  |  View Paper
In conclusion, insulin played the important role in bone lesion induced by excessive amount of fluoride through mediating InR receptor signaling, and IGF1 signaling probably exerted action on bone turnover caused by overdose of fluoride.
Biological Trace Element Research  •  2015  |  View Paper
Similarly, a combination treatment of a high dose of fluoride and STZ decreased insulin sensitivity and activity.
The results showed insulin combined with fluoride stimulated BMSC cell viability in vitro.
Biological Trace Element Research  •  2015  |  View Paper
Garcia-Montalvo et al.2 have shown that fluoride exposure impairs glucose tolerance via decreased insulin expression and oxidative stress.
Journal of the science of food and agriculture  •  2013  |  View Paper
In addition to inhibiting the glycolysis and depriving islets of energy essential for the biosynthesis of insulin, fluoride probably exerts a direct inhibitory influence on the biosynthetic mechanism.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme  •  1976  |  View Paper