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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
supplement:
Fluorides
drug:
Indomethacin
Research Papers that Mention the Interaction
“Methylene blue, indomethacin , N-ethylmaleimide, pertussis toxin and cholera toxin all significantly attenuated the endothelium-dependent relaxation caused by fluoride.”
Fluoride produces endothelium-dependent relaxation and endothelium-independent contraction in coronary artery.“In isolated rat … bladder, indomethacin inhibited the synthesis of the prostaglandins (PG) PGI2, PGE2, PGF2 alpha and … PG synthesis was stimulated with excitatory receptor agonists (noradrenaline and carbachol), fluoride (a G protein activator), phorbol ester (a protein kinase C (…) and calcium ionophore A23187 (a creator of artificial calcium channels).”
Differential inhibitory potencies of non-steroidal antiinflammatory drugs on smooth muscle prostanoid synthesis.
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