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Last Updated: 2 months ago

Possible Interaction: Fluorides and Glutathione

supplement:

Fluorides

supplement:

Glutathione

Research Papers that Mention the Interaction

Interestingly, antioxidants (vitamin E and glutathione ) can attenuate the inhibition of the receptor induced by fluoride.
Toxicology in vitro : an international journal published in association with BIBRA  •  2008  |  View Paper
When fluoride concentration increased to 20 mg/L, the toxic effect generated by fluoride led to a reduction of chlorophyll, protein, and carbohydrates in H. verticillata, but the activity of guaiacol peroxidase and SOD and the amount of ascorbic acid (AsA) and glutathione ( GSH ) were enhanced significantly.
International journal of phytoremediation  •  2018  |  View Paper
fluoride in excess of 12 mg/kg induced renal oxidative damage, which was characterized by increasing the levels of … carbonyls (PC), and decreasing the abilities of anti-superoxide anion (ASA) and anti-hydroxyl radical (AHR), glutathione ( GSH ) content, as well as activities and … (GR) and glutathione peroxidase (GSH-Px).
Oncotarget  •  2017  |  View Paper
fluoride in excess of 12 mg/kg induced renal oxidative damage, which was characterized by increasing the levels of … carbonyls (PC), and decreasing the abilities of anti-superoxide anion (ASA) and anti-hydroxyl radical (AHR), glutathione ( GSH ) content, as well as activities and … (GR) and glutathione peroxidase (GSH-Px).
Oncotarget  •  2017  |  View Paper
The fluoride exposure significantly elevated the level of LPO, CAT, SOD, and GST in the tissues of treated group as well as modulated the activities of GSH and level of GPx after exposure as compared to the control.
Toxicology international  •  2015  |  View Paper
This transport is inhibited by vanadate, fluoride and other inhibitors of glutathione S-conjugate transport in mammalian cells suggesting a similarity of this process to that known in eukaryotes.
Biochemistry and molecular biology international  •  1997  |  View Paper
A stoichiometric ratio of 2 was found between the amount of glutathione utilized and the amount of fluoride generated in the reaction.
Research communications in chemical pathology and pharmacology  •  1982  |  View Paper
A significant decrease in the levels of enzymatic (SOD2, CAT, GPx, and GSTpi class) and nonenzymatic GSH and Vitamin C) antioxidants along with increased ROS, lipid peroxidation, protein carbonyl content, and nitrate levels by fluoride were also prevented in these groups.
BioFactors  •  2015  |  View Paper
Fluoride induced oxidative stress through depletion in levels of various anti-oxidants such as glutathione , superoxide dismutase (SOD), fat soluble vitamins (D and E) with increased levels of lipid peroxidation (LPO) and fluoride aggravate the damage in rodents as well as in humans.
International Journal of Developmental Neuroscience  •  2015  |  View Paper
Additionally, fluoride perturbed GSH content and markedly reduced SOD, GPx, GR and CAT activities in brain tissues.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association  •  2014  |  View Paper
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