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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Flunitrazepam
supplement:
Taurine
Research Papers that Mention the Interaction
“In unwashed … membranes taurine produced an inhibition of [3H]flunitrazepam [( 3H]FNZ) binding with IC50 ranging between 31.5 and 11.9 microM; the IC20 varied between 18 and 26 nM. This inhibitory effect was of a mixed type, with a reduction in Bmax and an increase in KD.”
Taurine modulation of the benzodiazepine-gamma-aminobutyric acid receptor complex in brain membranes.“ Taurine displaced GABA from its receptor sites and inhibited GABA stimulation of flunitrazepam binding to receptor complexes solubilized with Triton X-100.”
Actions of taurine on the GABA-benzodiazepine receptor complex solubilized from rat brain
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