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Discover Supplement-Drug Interactions

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Possible Interaction: Flunitrazepam and Taurine



Research Papers that Mention the Interaction

In unwashed … membranes taurine produced an inhibition of [3H]flunitrazepam [( 3H]FNZ) binding with IC50 ranging between 31.5 and 11.9 microM; the IC20 varied between 18 and 26 nM. This inhibitory effect was of a mixed type, with a reduction in Bmax and an increase in KD.
Journal of neurochemistry  •  1984  |  View Paper
Taurine displaced GABA from its receptor sites and inhibited GABA stimulation of flunitrazepam binding to receptor complexes solubilized with Triton X-100.
Neurochemistry International  •  1987  |  View Paper