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Discover Supplement-Drug Interactions

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Last Updated: 2 months ago

Possible Interaction: Flunitrazepam and Progesterone

Research Papers that Mention the Interaction

Estradiol benzoate (2 µg) prevented the potentiation of flunitrazepam binding by NaCl in nonstressed and stressed animals, whereas progesterone (0.5 mg) increased the NaCl-induced potentiation of flunitrazepam binding in both nonstressed and stressed animals.
Psychopharmacology  •  2005  |  View Paper
In vivo administration of the sex steroids estradiol and progesterone induced a significant change in [3H]flunitrazepam (benzodiazepine agonist) binding levels in the amygdala, and cortico and posterior brain nuclei of the female rat.
Neuroendocrinology  •  1993  |  View Paper
The administration of 4 mg of progesterone , but not 1 mg, increased the binding of [3H]flunitrazepam in the basolateral amygdaloid nucleus and in the oriens-pyramidalis CA1 layer of the hippocampus.
European journal of pharmacology  •  1989  |  View Paper
In vivo progesterone enhanced flunitrazepam binding in the substantia gelatinosa while 10(-8) M progesterone in vitro was without effect.
Neuroscience  •  1988  |  View Paper