Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 months ago

Possible Interaction: Flunitrazepam and NAD

supplement:

NAD

Research Papers that Mention the Interaction

All the studied benzodiazepines (phenazepam, nitrazepam, clonazepam, flunitrazepam ) are able to displace [14C] NAD from its receptor sites, the mixed type of inhibition being manifested.
Ukrainskii biokhimicheskii zhurnal  •  1991  |  View Paper
It was shown that nicotinamide and NAD inhibit the specific binding of [3H]flunitrazepam to benzdiazepine receptors without causing a direct influence of gamma-aminobutyric acid (GABA) receptors.
The Kd value for the membrane-bound benzdiazepine receptor is 2.9 nM. NAD inhibited the specific binding of [3H]flunitrazepam to the solubilized membrane preparation when used at concentrations by several orders of magnitude lower than that of nicotinamide.
Biokhimiia  •  1989  |  View Paper