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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Flunitrazepam
supplement:
Melatonin
Research Papers that Mention the Interaction
“These results show that, although the benzodiazepine flunitrazepam improves sleep, it reduces the nocturnal secretion of melatonin , and therefore alters the circadian rhythm of a hormone which is supposed to play a special role in circadian sleep-wake rhythmicity.”
Nocturnal plasma melatonin levels after flunitrazepam administration in healthy subjects
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