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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Flunarizine
supplement:
Gamma-Aminobutyric Acid
Research Papers that Mention the Interaction
“Drugs suggested to affect membrane properties, such as chlorpromazine, was without effect at 1 or 10 microM, whereas flunarizine (FLU) at 1 microM inhibited both L-C (24%) and GABA uptake (17%).”
Structural, metabolic and ionic requirements for the uptake of L-carnitine by primary rat cortical cells.“Additionally, 10 microM flunarizine directly antagonises ouabain-induced tetrodotoxin (TTX)-sensitive Na+ influx, glutamate, aspartate and GABA release from synaptosomes, whilst inhibiting veratridine-induced Ca(2+)-independent TTX-sensitive Na+ influx and glutamate release at 15 microM and 10 microM in cells and synaptosomes, respectively.”
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