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Discover Supplement-Drug Interactions

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Last Updated: 2 months ago

Possible Interaction: Flumazenil and 4-Hydroxybutyric Acid

Research Papers that Mention the Interaction

Our previous studies revealed the ability of flumazenil (a benzodiazepine antagonist) to counteract GHB effects on GH secretion.
International clinical psychopharmacology  •  1995  |  View Paper
GHBA induced a significant increase in GH plasma levels; flumazenil pretreatment antagonized GHBA action on GH secretion.
The benzodiazepine receptor antagonist flumazenil was able to influence the sensitivity and the neuroendocrine consequences of GHBA binding site stimulation.
International clinical psychopharmacology  •  1994  |  View Paper
Diazepam (10 microM) or GHB (100 mM) prevented the increase in the amount of the alpha(4) subunit mRNA, the metabolic impairment, and the positive action of flumazenil induced by ethanol withdrawal but failed to restore the expression of the alpha(1) and gamma(2) subunits.
Molecular pharmacology  •  2003  |  View Paper