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Discover Supplement-Drug Interactions

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Last Updated: 4 months ago

Possible Interaction: Flufenamic Acid and Calcium Supplement

Research Papers that Mention the Interaction

Three TAS2R14 agonists, flufenamic acid , chlorhexidine, and diphenhydramine, also evoked rises in intracellular calcium in TCL.
American journal of physiology. Regulatory, integrative and comparative physiology  •  2019  |  View Paper
Flufenamic acid commonly not only affects non-selective cation channels and chloride channels, but also modulates potassium, calcium and sodium channels with effective concentrations ranging from 10(-6)M in TRPM4 channel inhibition to 10(-3)M in two-pore outwardly rectifying potassium channel activation.
Pharmacology & therapeutics  •  2013  |  View Paper
It requires an increase in postsynaptic calcium for activation, and is blocked by flufenamic acid , an antagonist of a previously identified calcium activated non-selective cation channel (I(CAN)).
Brain Research  •  2010  |  View Paper
In contrast flufenamic acid (100 microM), an inhibitor of non-selective cation channels, genistein (10 microM), a broad-range tyrosine kinase inhibitor, and piceatannol (10 microM), an inhibitor specific for non-receptor Syk tyrosine kinase, inhibited CCE during ACh decay but not during Ca2+ reintroduction.
The Journal of physiology  •  1999  |  View Paper