supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 months ago
drug:
Flufenamic Acid
supplement:
Calcium Supplement
Research Papers that Mention the Interaction
“Three TAS2R14 agonists, flufenamic acid , chlorhexidine, and diphenhydramine, also evoked rises in intracellular calcium in TCL.”
Cholecystokinin, gastrin, cholecystokinin/gastrin receptors, and bitter taste receptor TAS2R14: trophoblast expression and signaling.“ Flufenamic acid commonly not only affects non-selective cation channels and chloride channels, but also modulates potassium, calcium and sodium channels with effective concentrations ranging from 10(-6)M in TRPM4 channel inhibition to 10(-3)M in two-pore outwardly rectifying potassium channel activation.”
Flufenamic acid as an ion channel modulator.“It requires an increase in postsynaptic calcium for activation, and is blocked by flufenamic acid , an antagonist of a previously identified calcium activated non-selective cation channel (I(CAN)).”
Muscarinic receptor activation modulates the excitability of hilar mossy cells through the induction of an afterdepolarization“In contrast flufenamic acid (100 microM), an inhibitor of non-selective cation channels, genistein (10 microM), a broad-range tyrosine kinase inhibitor, and piceatannol (10 microM), an inhibitor specific for non-receptor Syk tyrosine kinase, inhibited CCE during ACh decay but not during Ca2+ reintroduction.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback