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The journals of gerontology. Series A, Biological sciences and medical sciences • 2003 | View Paper
“ Fludrocortisone exerted a significant inhibition of ACTH , cortisol and 11-desoxycortisol (p < 0.05), whereas no such effect was observed after aldosterone or placebo.”
“Whereas administration of fludrocortisone induced a significant inhibitory effect on basal ACTH and cortisol secretion, no considerable effects on sleep pattern were detectable.”
“ FC induced a dose-related trend toward a further decrease of the ACTH and cortisol levels, while it showed a significant and dose-dependent inhibition of the hormonal response to hCRH (p < 0.05 for the doses of 0.3, 0.1 and 0.075 mg).”