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Discover Supplement-Drug Interactions
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Last Updated: 2 months ago
drug:
Fluconazole
supplement:
Progesterone
Research Papers that Mention the Interaction
“Using the GFP-reporter strain, we show CDR1 induction by female but not male human serum and demonstrate that exposure of C. albicans to physiological concentrations of progesterone measurably increases resistance to fluconazole , miconazole and 5-fluorouracil.”
Key physiological differences in Candida albicans CDR1 induction by steroid hormones and antifungal drugs“Additionally, progesterone reduced the susceptibility of biofilm cells to fluconazole , consistent with an up-regulation of efflux pumps.”
Effect of progesterone on Candida albicans biofilm formation under acidic conditions: A transcriptomic analysis.
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