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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Fluconazole and Isoquercetin

supplement:

Isoquercetin

Research Papers that Mention the Interaction

ISO at non‐antifungal concentration interacts synergistically with amphotericin B (AMB) and fluconazole (FLC), but the combination with flucytosine (5‐FC) showed no interaction.
ISO combined with FLC caused metacaspase activation and DNA condensation, markers of apoptosis, higher than the combination with ISO/AMB.
In conclusion, AMB and FLC enhanced the antifungal potency of ISO through oxidative stress when used in synergy.
IUBMB life  •  2019  |  View Paper