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Discover Supplement-Drug Interactions

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Last Updated: 2 months ago

Possible Interaction: Fluconazole and Isoquercetin

supplement:

Isoquercetin

Research Papers that Mention the Interaction

ISO at non-antifungal concentration interacts synergistically with amphotericin B (AMB) and fluconazole (FLC), but the combination with flucytosine (5-FC) showed no interaction.
ISO combined with FLC caused metacaspase activation and DNA condensation, markers of apoptosis, higher than the combination with ISO/AMB.
In conclusion, AMB and FLC enhanced the antifungal potency of ISO through oxidative stress when used in synergy.
IUBMB life  •  2019  |  View Paper