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Discover Supplement-Drug Interactions

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Last Updated: 2 months ago

Possible Interaction: Fluconazole and Geraniol

supplement:

Geraniol

Research Papers that Mention the Interaction

Geraniol , geranyl acetate and citronellol brought down MICs of FLC by 16-, 32- and 64-fold respectively in a FLC-resistant strain.
Mycoses  •  2011  |  View Paper
The combination of EO, linalool, or geraniol with fluconazole enhanced their antifungal activity, especially against the resistant strain (MIC reduced to 156, 197, and 38 μg/mL, resp.).
Evidence-based complementary and alternative medicine : eCAM  •  2016  |  View Paper
Interestingly, Ger was synergistic (FICI<0.5) with fluconazole (FLC) which is a well known antifungal drug.
Together, modulation of efflux pump activity by Ger and FLC synergism represent a promising approach for combinatorial treatment of candidiasis.
PloS one  •  2018  |  View Paper