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Discover Supplement-Drug Interactions

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Last Updated: 2 months ago

Possible Interaction: Fluconazole and Epigallocatechin Gallate

Research Papers that Mention the Interaction

Against the biofilm, the susceptibility of fluconazole/ketoconazole significantly increased (3 to 5 fold), after combination with EGCG (MBIC/4) (P≤0.001).
The combination of EGCG with fluconazole/ketoconazole exhibited synergistic effects (ΣFICI≤0.50).
Journal de mycologie medicale  •  2019  |  View Paper
CONCLUSIONS We conclude that EGCG enhances the antifungal effects of miconazole, fluconazole and amphotericin B. Combined treatment with EGCG may lower the dosages of antimycotics, thus preventing adverse effects and the emergence of drug-resistant oral Candida species.
CONCLUSIONS We conclude that EGCG enhances the antifungal effects of miconazole, fluconazole and amphotericin B. Combined treatment with EGCG may lower the dosages of antimycotics, thus preventing adverse effects and the emergence of drug-resistant oral Candida species.
RESULTS Synergism was observed between EGCG and miconazole, fluconazole or amphotericin B against most test planktonic and biofilm cells of Candida species (FIC≤0.5).
RESULTS Synergism was observed between EGCG and miconazole, fluconazole or amphotericin B against most test planktonic and biofilm cells of Candida species (FIC≤0.5).
Archives of oral biology  •  2015  |  View Paper
These activities of EGCg were approximately 4-fold higher than those of fluconazole , and were 4 to 16-fold higher than flucytosin.
Yonsei medical journal  •  2011  |  View Paper
CONCLUSIONS These results indicate that EGCg enhances the antifungal effect of amphotericin B or fluconazole against antimycotic-susceptible and -resistant C. albicans.
CONCLUSIONS These results indicate that EGCg enhances the antifungal effect of amphotericin B or fluconazole against antimycotic-susceptible and -resistant C. albicans.
The Journal of antimicrobial chemotherapy  •  2004  |  View Paper