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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
drug:
Fluconazole
supplement:
Epigallocatechin Gallate
Research Papers that Mention the Interaction
“The combination of EGCG with fluconazole/ketoconazole exhibited synergistic effects (ΣFICI≤0.50).”
Synergistic effects of tea polyphenol epigallocatechin 3-O-gallate and azole drugs against oral Candida isolates.“These activities of EGCg were approximately 4-fold higher than those of fluconazole , and were 4 to 16-fold higher than flucytosin.”
In Vitro Antifungal Activity of Epigallocatechin 3-O-Gallate against Clinical Isolates of Dermatophytes“CONCLUSIONS These results indicate that EG g en hances the antifungal effect of amphotericin B or flu conazole ag ainst antimycotic-susceptible and -resistant C. albicans.”
“The combined use of 12.5 mg/L EGCg and fluconazole 10-50 mg/L (below MIC) inhibited the growth of fluconazole-resistant C. albicans by 98.5%-99.7%.”
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