Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago

Possible Interaction: Floxuridine and Folate

supplement:

Folate

Research Papers that Mention the Interaction

This reduced folate enhanced the cytotoxicity and the growth inhibitory potency of 5-fluorouracil ( 5-FUra ) and of 5-fluoro-2'-deoxyuridine (FUdR) against all cell lines examined.
Cancer research  •  1986  |  View Paper
The lack of sufficient folates in the tumor cell, especially N5,N10-methylene tetrahydrofolate, would thus result in less than optimal cell kill by FUdR and possibly by 5-FU.
Seminars in oncology  •  1983  |  View Paper
These results demonstrate that folate metabolism is important for the efficacy of FdUrd.
PloS one  •  2016  |  View Paper