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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
drug:
Fleroxacin
supplement:
Serum Albumin, Human
Research Papers that Mention the Interaction
“Fleroxacin (FLRX) is a new member of the class of fluoroquinolones, its effects … the mechanism of action are poorly understood, Especially, the secondary structural alterations of HSA … FLRX and the inner filter effect, which resulted in a spurious decrease … affected the binding parameters calculated from it are not considered.”
“From the synchronous fluorescence, … the binding of FLRX … HSA induced a conformational change in the protein, and the alterations of secondary structure were quantitatively calculated by the evidence from ….3%, decreases of β-sheet structures of about 9.6%, and increases of β-turn structures of about 18.0%.”
Spectroscopic and Molecular Modeling Studies on Binding of Fleroxacin with Human Serum Albumin.
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