Possible Interaction: Fish Oils and Nitric Oxide

“Dietary supplementation with fish oils has been shown to augment endothelium-dependent relaxations, principally by improving the release of nitric oxide from injured endothelium.”

“CONCLUSIONS NO increase and blood pressure reduction with fish oil or soy protein reinforce the importance of the influence of NO on blood pressure in patients with MS.”

“ CONCLUSIONS NO increase and blood pressure reduction with fish oil or soy protein reinforce the importance of the influence of NO on blood pressure in patients with MS.”

“RESULTS Serum nitric oxide metabolites showed significant increase after 90 days in the fish oil and soy groups.”

“ RESULTS Serum nitric oxide metabolites showed significant increase after 90 days in the fish oil and soy groups.”

“ Fish oil treatment decreased the serum levels of TNF α , IL-1 β , IL-6, and nitric oxide metabolites compared with placebo group (P ≤ 0.001).”

“RESULTS Supplementation with FO + WGO reduced MDA and NO ( P < 0.001) in diabetic rat brains and enhanced brain antioxidant capacity, as evidenced by increased GSH, GSH/GSSG ratio ( P < 0.01), and SOD and CAT activity ( P < 0.01).”

“ RESULTS Supplementation with FO + WGO reduced MDA and NO ( P < 0.001) in diabetic rat brains and enhanced brain antioxidant capacity, as evidenced by increased GSH, GSH/GSSG ratio ( P < 0.01), and SOD and CAT activity ( P < 0.01).”

“Our results support the concept that, in the hamster cheek pouch microcirculation, fish oil supplementation activates K(+) channels which act as the EDHF and might also increase the production of vasodilators, probably NO.”