Possible Interaction: Fish Oils and Interleukin-10

“Our results reveal that fish oil supplementation decreased secretory immunoglobulin A and increased IL-10 production in lactating women along with increased breast milk eicosapentaenoic acid, and this corresponded to increased abundances of fecal Bifidobacterium and Lactobacillus spp.”

“However, FO supplementation increased lymphocyte proliferation before and after the marathon, and before the race, FO supplementation decreased IL-2, TNF-α, and IL-10 production in concanavalin-A-stimulated lymphocytes (by 55%, 95%, and 58%, respectively) compared with cells from the C group.”

“Moreover, FO decreased the mRNA expression of IL-1β, IL -6, and TNF-α and increased the mRNA expression of IL-4 and IL-10 in the cortex and hippocampus.”

“The FD downregulated the expression of SOD, IL-1β, IL-6, and transforming growth factor-β-activated kinase 1 binding protein 1 (TAB1) mRNA but upregulated the expression of lipoxygenase enzyme 5 (ALOX5) and interleukin-10 (IL-10) mRNA in placentas (P < 0.05).”

“ FFO treatment did increase the expression of the immune-suppressive cytokines TGF-β and IL-10.”

“Intragastrical supplementation with 0.6% fish oil induced pronounced inhibition of the pro‐inflammtory cytokine expression of interleukin (IL)‐6 and tumor necrosis factor (TNF)‐α, and the increase of anti‐inflammtory cytokine expression of IL‐10 in graft.”