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Discover Supplement-Drug Interactions

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Last Updated: 2 months ago

Possible Interaction: Fish Oils and Fenofibrate

supplement:

Fish Oils

Research Papers that Mention the Interaction

AIDS Clinical Trials Group A5186 examined the safety and efficacy of fish oil plus fenofibrate in subjects not achieving serum TG levels < or =200 mg/dL with either agent alone.
AIDS Clinical Trials Group A5186 examined the safety and efficacy of fish oil plus fenofibrate in subjects not achieving serum TG levels < or =200 mg/dL with either agent alone.
Fish oil reduced TG levels by a median of 283 mg/dL (46%), fenofibrate reduced them by 367 mg/dL (58%), and combination therapy reduced them by 65.5%.
Journal of acquired immune deficiency syndromes  •  2008  |  View Paper
Significant overlap in gene regulation by fenofibrate and fish oil was observed, reflecting their property as high or low affinity agonist for peroxisome proliferator-activated receptor-α, respectively.
Physiological genomics  •  2011  |  View Paper
Although plasma total cholesterol levels fell significantly in fish oil-fed groups, fenofibrate treatments increased significantly plasma total cholesterol levels in these fish oil groups, but not in the group fed SO alone; however, hepatic triglyceride and total cholesterol levels markedly decreased in MO-or TO-fed mice.
Journal of atherosclerosis and thrombosis  •  2009  |  View Paper