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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Fish Oils
Research Papers that Mention the Interaction
“Thus, a small amount of FOC increased the effectiveness of DOX but did not increase the toxicity of DOX to the host mouse.”
Three percent dietary fish oil concentrate increased efficacy of doxorubicin against MDA-MB 231 breast cancer xenografts.“However, in those mice, which consumed FO or FO with ferric citrate, treatment with DOX caused significant tumor regression.”
“ Fish oil and vitamin E appeared to enhance the antitumor effect of optimal doses of DOX but to aggravate cardiotoxicity owing to DOX overdose.”
“On the other hand, DOX at 12.0 mg/kg induced severe heart damage, which was also significantly aggravated by both fish oil and vitamin E, as shown by both decreased LS and increased serum creatine phosphokinase activity.”
Dietary fish oil and vitamin E enhance doxorubicin effects in P388 tumor-bearing mice
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