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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Fexofenadine
supplement:
Grapefruit Extract
Research Papers that Mention the Interaction
“Fruit juices such as grapefruit , orange and apple juice may decrease the oral bioavailability of fexofenadine by inhibiting the activity of OATP1A2 [5].”
Fexofenadine pharmacokinetics are associated with a polymorphism of the SLCO1B1 gene (encoding OATP1B1).
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