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Last Updated: 3 years ago

Possible Interaction: Fexofenadine and Garlic

supplement:

Garlic

Research Papers that Mention the Interaction

Garlic increased the area under the curve0–∞ and maximum plasma concentration of orally administered fexofenadine by 47% and 85%, respectively.
In the perfused liver, garlic , ginkgo, and SJW increased the biliary clearance of fexofenadine with respect to perfusate by 71%, 121%, and 234%, respectively.
Induction of intestinal Oatp1a5 by garlic may explain the increased absorption of orally administered fexofenadine.
Drug Metabolism and Disposition  •  2017  |  View Paper