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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
supplement:
Ferrous
supplement:
Cobaltous Cation
Research Papers that Mention the Interaction
“All three isozymes were rapidly activated (13-40-fold) by incubation with Fe(II) salts (concentration of iron at half-maximal activation = 6-14 microM), and were inhibited by other divalent metal ions, e.g. Zn(II), Co(II ) and Ni(II).”
Recombinant human tyrosine hydroxylase isozymes. Reconstitution with iron and inhibitory effect of other metal ions.“ Co(II ) inhibited Fe(II) oxidation.”
Moving metal ions through ferritin-protein nanocages from three-fold pores to catalytic sites.“Foreign ions, such as Fe(II ), Cr(III) and Mn(II), interfere when present in more than 10-fold ratio to Co(II ), but several ions can be tolerated when present in higher ratios to Co(II).”
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