Possible Interaction: Ferric Oxide, Saccharated and Iron, Dietary

“Furthermore, pretreating cancer cells with iron sucrose enhanced DPEN toxicity while treating with deferoxamine, an Fe chelator that inhibits redox cycling, inhibited DPEN toxicity.”

“ Iron content in MCs exposed to dialysate obtained after IS infusion was increased by 32% (p < 0.01).”

“Results: Dialysate total iron was increased (+19%, p < 0.01) during intravenous infusion of IS.”

“Compared with controls, rats exposed to IS showed increased dialysate iron concentration by +70%, P<0.001, and in the differential cell count, more eosinophils (+113%, P<0.05) and fewer macrophages (-16%, P<0.05) existed.”

“… iron sucrose resulted in increased accumulation … glomeruli: + 38% at Fe 1 mg/kg bw P < 0.05 and + 42% at Fe 10 mg/kg/bw P < 0.01 and collagen … Fe 1 mg/kg bw P < 0.005 and + 77% at Fe 10 mg/kg/bw P < 0.001.”

“Richmond, Roy, Gardner, Alexander, and Duthie (1958) showed that a 5 g. course of saccharated oxide of iron , given intravenously to patients with rheumatoid arthritis, was followed not only by an increase in the haemoglobin concentration but also by a”

“Iron deposition in the unusual 12-subunit …(2)-P](Z+2) represents adinuclear iron(II) complex formed at each of the 12 ferroxidase centresof the protein; a second phase corresponding to oxidation …(+) [where FeOOH((s)) represents the hydrous ferric oxidemineral that precipitates from the solution], which occurs when iron ….”