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Discover Supplement-Drug Interactions

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Last Updated: 4 months ago

Possible Interaction: Fentanyl and Quinidine

supplement:

Quinidine

Research Papers that Mention the Interaction

Quinidine … oral fentanyl (3.4 ± 1.3 vs. 2.3 ± 1.3 mm, p < 0.05), commensurate with increases in plasma concentrations, but concentration‐effect relationships … the transfer between plasma and effect compartment (ke0) (1.9 ± 1.0 vs. 3.6 ± 2.6 h−1) were not significantly different.
Journal of clinical pharmacology  •  2004  |  View Paper
Quinidine , however, inhibited the binding of fentanyl to plasma proteins and red cells equally, to maintain a partition coefficient of unity.
The Journal of pharmacy and pharmacology  •  1982  |  View Paper