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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“Our hypothesis was that the addition of magnesium to postoperative epidural infusion of fentanyl may decrease the need for fentanyl.”
Epidural magnesium reduces postoperative analgesic requirement.“Coinjection of magnesium with fentanyl markedly enhanced the antinociception.”
“ Magnesium may not only prevent the hyperalgesia but also enhance antinociceptive effect of fentanyl.”
Magnesium modifies fentanyl-induced local antinociception and hyperalgesia“The fentanyl consumed in first 24 hours was significantly less in those patients who received lignocaine and magnesium [Group I (204.4 ± 136.4), Group II (383 ± 168.2), Group III (194 ± 148.9); (P = 0.01)].”
Effect of magnesium and lignocaine on post-craniotomy pain: A comparative, randomized, double blind, placebo-controlled study“The total postoperative consumption of fentanyl was significantly lower in the Magnesium group (42.4 ± 5.3) than that in the placebo group (94.4 ± 9.9), with a P value 0.”
“Reduced fentanyl and rocuronium consumption in Mg group are compared to C (P = 0.00).”
“Conclusions: The administration of magnesium (75 mg) as an adjuvant to epidural fentanyl (1 μg/ kg) for postoperative analgesia results in significantly lower VRS with prolonged duration of analgesia as compared with epidural fentanyl (1 μg/kg) alone.”
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