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Discover Supplement-Drug Interactions
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Last Updated: 2 months ago
Research Papers that Mention the Interaction
“Our hypothesis was that the addition of magnesium to postoperative epidural infusion of fentanyl may decrease the need for fentanyl. ”
Epidural magnesium reduces postoperative analgesic requirement.“The total postoperative consumption of fentanyl was significantly lower in the Magnesium group (42.4 ± 5.3) than that in the placebo group (94.4 ± 9.9), with a P value 0.”
Analgesic effect of adding magnesium sulfate to epidural levobupivacaine in patients with pre-eclampsia undergoing elective cesarean section“Conclusion Epidural magnesium , added to levobupivacaine and fentanyl as a single bolus dose effectively prolongs the duration of analgesia in high-risk cardiac patients undergoing peripheral vascular surgery.”
“CONCLUSIONS The administration of magnesium (75 mg) as an adjuvant to epidural fentanyl (1 μg/ kg) for postoperative analgesia results in significantly lower VRS with prolonged duration of analgesia as compared with epidural fentanyl (1 μg/kg) alone.”
“ Magnesium may not only prevent the hyperalgesia but also enhance antinociceptive effect of fentanyl.”
Magnesium modifies fentanyl-induced local antinociception and hyperalgesia
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