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Discover Supplement-Drug Interactions

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Last Updated: 2 months ago

Possible Interaction: Fentanyl and Gamma-Aminobutyric Acid

Research Papers that Mention the Interaction

Fentanyl (100 microM) infused for 25 min into the nucleus accumbens via the dialysis membrane produced a marked and transient increase in accumbens GABA concentration to a maximum of approximately 1200% at its peak effect that occurred at 25 min after cessation of the fentanyl infusion.
Journal of oral science  •  1998  |  View Paper
The centrally acting drugs belonging to different groups--fluphenazine, trifluperidol, phthoracyzine, imipramine, diazepam, apomorphine, fentanyl , diphneylhydantoin, nonachlazine displayed in vitro an inhibitory effect on the uptake of gamma-aminobutyric acid by rat brain synaptosomes.
Biulleten' eksperimental'noi biologii i meditsiny  •  1976  |  View Paper