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Last Updated: 2 years ago

Possible Interaction: Fentanyl and Calcium Supplement

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drug:

Fentanyl

supplement:

Calcium Supplement

Research Papers that Mention the Interaction

“ Fentanyl depresses myocardial contractility by decreasing the availability of intracellular Ca (2+) and myofilament Ca2+ sensitivity.”

Differential Effects of Fentanyl and Morphine on Intracellular Ca2+ Transients and Contraction in Rat Ventricular Myocytes

Anesthesiology • 1998 | View Paper

“Increases in plasma calcium concentration did not alter the contractile responses to sympathetic nerve stimulation but antagonized the inhibitory effect of fentanyl in a dose-dependent manner suggesting a possible competitive antagonism.”

Calcium antagonism of the inhibitory effects of fentanyl on the contraction of the nictitating membrane in cats.

European journal of pharmacology • 1981 | View Paper

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