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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
drug:
Fenofibrate
supplement:
Tretinoin
Research Papers that Mention the Interaction
“ConclusionThe combination of fenofibrate and retinoic acid is a potent inhibitor of Ishikawa endometrial cancer cell growth in vitro.”
In vitro and in vivo effects of the PPAR-alpha agonists fenofibrate and retinoic acid in endometrial cancer“Treatment with fenofibric acid counteracted the increase in apo A-I mRNA levels observed after dexamethasone or all-trans retinoic acid treatment, whereas simultaneous addition of fenofibric acid together with all-trans retinoic acid or dexamethasone resulted in a superinduction of acyl-CoA oxidase mRNA.”
Regulation of rat liver apolipoprotein A-I, apolipoprotein A-II and acyl-coenzyme A oxidase gene expression by fibrates and dietary fatty acids.“The anti-neoplastic effects of fenofibrate are especially more pronounced when used in conjunction with retinoic acid [3].”
Fenofibrate: direct attenuating effects on tumor growth
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