Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago

Possible Interaction: Fenfluramine and Oxytocin

supplement:

Oxytocin

Research Papers that Mention the Interaction

D-FEN was associated with an increase in both oxytocin and prolactin.
Psychiatry Research  •  2003  |  View Paper
Further, the administration of fenfluramine , a serotonergic agonist, to healthy subjects increases plasma OT levels.
European Neuropsychopharmacology  •  2012  |  View Paper
Using dual-immunocytochemistry, the number of oxytocinergic neurons in the hypothalamic magnocellular nuclei co-storing Fos after administration of D-fenfluramine was found to be 15-fold higher compared to vehicle, comprising about 30% of the total number of these neurons.
Brain Research  •  1999  |  View Paper
Fenfluramine (2 mg/kg ip) stimulated AVP, OT , corticosterone, and prolactin (PRL) secretion (P<0.01).
The American journal of physiology  •  1996  |  View Paper
Oxytocin secretion was more potently stimulated by d-fenfluramine than by l-fenfluramine.
The d- and l-stereoisomers of the 5-HT releaser fenfluramine significantly increased plasma oxytocin in a dose-dependent manner.
The Journal of pharmacology and experimental therapeutics  •  1991  |  View Paper