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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Fenfluramine and Gamma-Aminobutyric Acid

Research Papers that Mention the Interaction

Transmitters other than serotonin such as acetylcholine, catecholamines and GABA are also affected by systemic administration of fenfluramine , but some of these effects are secondary to fenfluramine's action on serotoninergic mechanisms.
Appetite  •  1986  |  View Paper
Even though fenfluramine produced a small reduction in the uptake of dopamine, γ-aminobutyric and glutamic acids 4 hr after injection, this effect disappeared 1 day later.
In vitro, addition of fenfluramine into a synaptosomal fraction reduced uptake of 5-hydroxytryptamine, dopamine, γ-aminobutyric acid , glutamic acid, tryptophan and tjrosine. [
Neuropharmacology  •  1976  |  View Paper