supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago
drug:
Fenfluramine
supplement:
Adrenocorticotropic Hormone
Research Papers that Mention the Interaction
“The 5-HT releaser fenfluramine raises body temperature as well as plasma concentrations of ACTH , cortisol, and prolactin.”
Downregulation of serotonin receptor subtypes by nortriptyline and adinazolam in major depressive disorder: neuroendocrine and platelet markers.“There was a significant dose-dependent stimulatory effect of fenfluramine on both ACTH and cortisol levels.”
“The ACTH response to FEN was significantly reduced at 4 and 8 months in both MDMA treatment groups, and at 12 months in the multiple dose group only.”
“The corticotropin (ACTH) response to FEN (6 and 8 mg/kg) was blunted and the prolactin response to FEN (4 and 6 mg/kg) was enhanced in MDMA pre-treated rats.”
Abnormal ACTH and prolactin responses to fenfluramine in rats exposed to single and multiple doses of MDMA
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback