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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
drug:
Fenfluramine
supplement:
Adrenocorticotropic Hormone
Research Papers that Mention the Interaction
“The 5-HT releaser fenfluramine raises body temperature as well as plasma concentrations of ACTH , cortisol, and prolactin.”
Downregulation of serotonin receptor subtypes by nortriptyline and adinazolam in major depressive disorder: neuroendocrine and platelet markers.“There was a significant dose-dependent stimulatory effect of fenfluramine on both ACTH and cortisol levels.”
“The ACTH response to FEN was significantly reduced at 4 and 8 months in both MDMA treatment groups, and at 12 months in the multiple dose group only.”
“The corticotropin (ACTH) response to FEN (6 and 8 mg/kg) was blunted and the prolactin response to FEN (4 and 6 mg/kg) was enhanced in MDMA pre-treated rats.”
Abnormal ACTH and prolactin responses to fenfluramine in rats exposed to single and multiple doses of MDMA
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