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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Felodipine
supplement:
Quercetin
Research Papers that Mention the Interaction
“A 50-gmol/1 concentration of quercetin inhibited approximately 70% of felodipine and 50% of nifedipine metabolism.”
“In mechanistic in vitro studies with human liver microsomes, quercetin has been shown to be the most potent inhibitor of nifedipine and felodipine metabolism [7].”
Quercetin not only inhibits P-glycoprotein efflux activity but also inhibits CYP3A isozymes
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