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Discover Supplement-Drug Interactions

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Last Updated: 18 days ago

Possible Interaction: Felodipine and Calcium Supplement

Research Papers that Mention the Interaction

The plasma calcium concentration was significantly higher during felodipine treatment than during placebo and this was accompanied by an increased urinary calcium excretion.
Methods and findings in experimental and clinical pharmacology  •  1987  |  View Paper
The effect of calcium (Ca2+) antagonism with felodipine on the intracellular concentrations and transmembrane fluxes of cations in erythrocytes, was studied in 10 normal volunteers at rest and during exercise.
Journal of hypertension  •  1986  |  View Paper
Felodipine is a dihydropyridine that blocks the slow entry channel for calcium.
Journal of cardiovascular pharmacology  •  1990  |  View Paper
The negative myocardial effect of felodipine , attainable only in vitro, is characterised by surmountable antagonism of the inotropic response to added adrenergic agonists or Ca2+ and is compatible with calcium influx inhibition.
Drugs  •  2012  |  View Paper
Felodipine inhibited the initial rate of ATP-driven calcium uptake but failed to affect the initial rate of mitochondrial calcium transport.
Cardiovascular Drugs and Therapy  •  2004  |  View Paper
Inhibition of intracellular calcium increases wasachieved using nM concentrations of felodipine or amlodipine.
Pharmaceutical Research  •  2004  |  View Paper
Compared with vehicle alone, felodipine significantly increased NOx generation, Ca2+ -dependent NOS activity, and eNOS protein mass in proliferating and quiescent endothelial cells.
Hypertension  •  1998  |  View Paper
Felodipine inhibited both L-type Ca2+ channel currents (ICa) and cell contractions in a concentration-dependent manner (10 pM to 100 nM) when we used a holding potential of -80 mV or -40 mV. The potency of felodipine was sharply dependent on a holding potential.
European journal of pharmacology  •  1997  |  View Paper
Felodipine (100 nM) caused a gradual decrease in the amplitude of the spontaneous phasic contractions in a calcium-containing medium.
European journal of pharmacology  •  1988  |  View Paper
Felodipine selectively decreased the sustained, but not the transient, type of calcium current in a whole-cell voltage clamp of azygos venous muscle cells.
Journal of cardiovascular pharmacology  •  1987  |  View Paper
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