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Discover Supplement-Drug Interactions

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Last Updated: 2 months ago

Possible Interaction: Fatty Acids, Omega-3 and Tamoxifen

Research Papers that Mention the Interaction

Furthermore, administration of omega-3 fatty acids allows the use of lower and, hence, likely less toxic doses of Tamoxifen.
Our preclinical data indicate that the administration of omega-3 fatty acids potentiates the antitumor effects of Tamoxifen by inhibiting multiple proliferative and antiapoptotic pathways, several of which interact with estrogen receptor signaling.
The complementarity in the mechanism of antitumor action of Tamoxifen and omega-3 fatty acids is well supported by our signaling, genomic, and proteomic studies.
BioMed research international  •  2015  |  View Paper
Preclinical data indicate that omega-3 fatty acids (n-3FA) potentiate the chemopreventive effect of the antiestrogen (AE) tamoxifen against mammary carcinogenesis.
Cancer Prevention Research  •  2015  |  View Paper