Possible Interaction: Fatty Acids, Omega-3 and Polyunsaturated Fatty Acids

“Serum levels of IL-1β and TNF-α were reduced after omega-3 PUFA supplementation (-72% for IL-1β; -56% for TNF-α; both, P < .05) in obese but not in NW women.”

“Our findings support the recommendation that the omega-3 PUFA dose be higher in CVD than among healthy subjects.”

“Thus, 4-week supplementation of 640 mg omega-3 PUFA reduced measures of platelet aggregation and activation in healthy subjects but effects were less evident in patients with existing CVD.”

“…,omega-3 PUFA significantly reduced adenosine diphosphate (ADP)-induced (maximum amplitude, 77.0% ± 3.2% vs. 71.6% ± 3.4%, p = 0.036; maximum slope, 86.… vs. 37.4 ± 3.0, p = 0.013; lag time, 00:21 ± 00:02 vs. 00:31 ± 00:03 s, p = 0.002).”

“The low intake of omega-3 PUFA likely contributed, in part, to the majority of players having an O3i of less than 8%.”

“The investigators reported that total long-chain omega-3 PUFAs were significantly inversely associated with risk of exercised-induced ischaemia, with …”

“We have recently observed that the high consumption of omega-6 PUFA results in significant attenuation of the beneficial effect of omega-3 PUFA on MI.”

“This resulted in reduced omega-3 polyunsatureated fatty acids in the brain.”

“Recently, decreased risk of first clinical diagnosis of CNS demyelination associated with higher intake of omega-3 polyunsaturated fatty acids particularly originating from fish was reported.”

“BACKGROUND AND OBJECTIVES The consumption of fish and long chain omega-3 polyunsaturated fatty acids (n-3 PUFA) may influence the risk of all-cause mortality, but the findings have been inconsistent.”

“However, a body of literature demonstrates an inverse correlation between omega-3 polyunsaturated fatty acid levels and quality of life/ psychiatric diseases.”

“Despite increased consumption of PUFA at the present time the ratio of omega-6 and omega-3 fatty acids in the diet is not optimal.”