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Discover Supplement-Drug Interactions

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Last Updated: 2 months ago

Possible Interaction: Fatty Acids, Omega-3 and Phospholipids

Research Papers that Mention the Interaction

The proportion of total n-3 fatty acids in the muscle phospholipids was approximately 2.5 times higher, with a 5 times higher proportion of eicosapentaenoic acid (20:5n-3), in subjects supplemented with n-3 fatty acids than in those given placebo.
The American journal of clinical nutrition  •  2002  |  View Paper
RESULTS Supplementation with n-3 fatty acids was associated with 26% lower serum triacylglycerol concentrations (P < 0.0001), a 28% lower overall ratio of serum triacylglycerol to HDL cholesterol (P < 0.01), and markedly greater EPA and DHA concentrations in serum phospholipids (P < 0.05).
RESULTS Supplementation with n-3 fatty acids was associated with 26% lower serum triacylglycerol concentrations (P < 0.0001), a 28% lower overall ratio of serum triacylglycerol to HDL cholesterol (P < 0.01), and markedly greater EPA and DHA concentrations in serum phospholipids (P < 0.05).
The American journal of clinical nutrition  •  2000  |  View Paper
The extra amount of n-3 fatty acids consumed by the mothers resulted in higher contents of n-3 fatty acids, and of docosahexaenoic acid (22:6n-3) in particular, in the phospholipids of umbilical plasma and vessel walls.
The British journal of nutrition  •  1995  |  View Paper
RESULTS In the fish-oil group, n-3 fatty acids were increased in serum phospholipids (P < 0.001), the ratio of arachidonic acid to eicosapentaenoic acid decreased (P < 0.001), and the level of n-6 fatty acids decreased (P < 0.001).
RESULTS In the fish-oil group, n-3 fatty acids were increased in serum phospholipids (P < 0.001), the ratio of arachidonic acid to eicosapentaenoic acid decreased (P < 0.001), and the level of n-6 fatty acids decreased (P < 0.001).
The New England journal of medicine  •  1993  |  View Paper
The decreases in blood pressure were larger as concentrations of plasma phospholipid n-3 fatty acids increased (P = 0.027).
The New England journal of medicine  •  1990  |  View Paper
The data of Herbst et al. (…) show that 12 weeks of omega-3 supplementation leads to a remodelling of the mitochondrial membrane … significant incorporation of omega-3 fatty acids into various phospholipid species at the expense of omega-6 fatty acids, despite no change in the total lipid pool.
The Journal of physiology  •  2014  |  View Paper
Omega-3 fatty acids have anti-inflammatory properties and can alter central nervous system cell membrane fluidity and phospholipid composition.
Journal of the American Academy of Child and Adolescent Psychiatry  •  2011  |  View Paper
The incorporation of n-3 polyunsaturated fatty acids (PUFAs) into membrane phospholipids may diminish inflammatory potential in patients with gastrointestinal diseases.
European Journal of Clinical Nutrition  •  2010  |  View Paper
CONCLUSIONS Diet and n-3 fatty acid supplementation dramatically reduced serum triglycerides, decreased arachidonic acid in the phospholipids fraction , and appeared to decrease the de novo lipogenesis associated with the metabolic syndrome in the intervention group.
The American journal of clinical nutrition  •  2009  |  View Paper
This may be linked to higher serum concentrations of n-3 fatty acids , which promote a favorable composition of phospholipids.
The American journal of clinical nutrition  •  2006  |  View Paper
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