Possible Interaction: Fatty Acids, Omega-3 and Linolenic Acid

“CONCLUSION In obese children a six-week-long supplementation of the diet with 1000 mg alpha-linolenic acid per day increased significantly the contribution of omega-3 fatty acids only to the non-esterified fatty acids of plasma lipids, but had no significant effect on the esterified fractions.”

“ CONCLUSION In obese children a six-week-long supplementation of the diet with 1000 mg alpha-linolenic acid per day increased significantly the contribution of omega-3 fatty acids only to the non-esterified fatty acids of plasma lipids, but had no significant effect on the esterified fractions.”

“CONCLUSIONS The results of the present study suggest the presence of competitive interactions between n-3 fatty acids (ALA) and n-6 fatty acids ( GLA and DTA).”

“ CONCLUSIONS The results of the present study suggest the presence of competitive interactions between n-3 fatty acids (ALA) and n-6 fatty acids ( GLA and DTA).”

“Subgroup analysis indicated that omega-3 fatty acid supplementation was associated with a reduction in total mortality risk if the proportion of men in the study population was more than 80%, or participants received alpha-linolenic acid.”

“This simple point remains highly debated despite evidence that removal of dietary ALA promotes n-3 fatty acid inadequacy, including that of docosahexaenoic acid (DHA), and that many experiments demonstrate that dietary inclusion of ALA raises n-3 tissue fatty acid content, including DHA.”

“CONCLUSIONS In the context of a diet rich in oleic acid, poor in saturated fats … fatty acids (a dietary pattern characterising the traditional Mediterranean diet), even small doses of omega-3 fatty acids (about 1 g EPA+DHA … capsules or 2 g alpha-linolenic acid in canola … very protective.”

“ CONCLUSIONS In the context of a diet rich in oleic acid, poor in saturated …-6 fatty acids (a dietary pattern characterising the traditional Mediterranean diet), even small doses of omega-3 fatty acids (about 1 g EPA+DHA … capsules or 2 g alpha-linolenic acid in canola … very protective.”

“as are found in vegans or in the diet of omnivores in Western societies, would tend to slow down the formation of long-chain omega-3 fatty acids from ALA.”

“It is only when omega-3 fatty acids , alpha-linolenic acid (ALA), or eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) were added to the diet that sudden cardiac death ( ALA , EPA plus DHA) and nonfatal myocardial infarction (only ALA) were significantly lowered.”

“ omega-3 Linolenic acid significantly, but reversibly, inhibited growth at 1.8, 2.5, and 5 x 10(-4) M (p < 0.01), while concentrations of 10(-3) M killed virtually all organisms, with cell lysis observed by electron microscopy.”

“Our results suggest that omega-3 linolenic acid counteracts the elevation of TRF1 levels, which increase with age and due to the presence of reactive oxygen species in muscle.”

“Enrichment of omega-3 fatty acids indicated a significant increase in fatty acid bioconversion ( ALA 32.2 ± 0.42%, EPA 7.9 ± 0.1%, and DHA 4.09 ± 0.2%) by 2.5-fold.”