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Last Updated: 2 months ago

Possible Interaction: Fatty Acids, Omega-3 and Leptin

Research Papers that Mention the Interaction

Our analysis showed that omega-3 supplementation significantly reduces leptin levels (mean difference (MD) = -1·71 ng/ml 95% confidence interval (CI): -3·17 to -0·24, P = 0·022).
Subgroup analysis based … showed that the omega-3 … leptin when used for nonobese subjects (MD = -3·60 ng/ml; 95% CI -6·23 to -0·90; P = 0·011); … not true for obese participants (MD = -0·86 ng/ml; 95% CI: -2·63 to -0·90; P = 0·296).
Clinical endocrinology  •  2015  |  View Paper
Omega-3 was observed to decrease circulating levels of leptin in non-obese subjects; however, omega-3-associated increases in leptin levels have been observed in obese subjects.
The Journal of pediatrics  •  2015  |  View Paper
Omega-3 was observed to decrease circulating levels of leptin in non-obese subjects; however, omega-3-associated increases in leptin levels have been observed in obese subjects.
The Journal of pediatrics  •  2015  |  View Paper
In a review by Gray et al., omega-3 is observed to decrease circulating levels of leptin in non-obese subjects while omega-3-associated increases in leptin levels have been claimed in obese subjects [5].
Second, as mentioned in many studies, dietary intake of some food groups and supplements including fatty acids (particularly omega-3 fatty acid ) can affect plasma leptin levels [5].
World Journal of Surgery  •  2014  |  View Paper
BackgroundThe expression of leptin is increased in obesity and inhibited by n-3 polyunsaturated fatty acids (n-3 PUFAs), but the underlying molecular mechanisms have not been firmly established.
Nutrition & metabolism  •  2011  |  View Paper
In non-obese subjects, omega-3 is observed to decrease circulating levels of leptin ; however, omega-3-associated increases in leptin levels have been observed in obese subjects.
European Journal of Clinical Nutrition  •  2013  |  View Paper
Oleic acid or n-3 fatty acids downregulate the expression of leptin , fatty acid synthase and lipoprotein lipase in retroperitoneal adipose tissue.
Acta veterinaria Hungarica  •  2007  |  View Paper