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Discover Supplement-Drug Interactions

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Last Updated: 2 months ago

Possible Interaction: Fatty Acids, Omega-3 and Celecoxib

Research Papers that Mention the Interaction

Individual and combined administration of celecoxib and omega-3 fatty acid significantly increased OC levels compared to the LPS group (P <0.05).
The significantly increased serum OC level observed after individual and combination administration suggests that celecoxib and omega-3 fatty acid may influence bone remodeling and thereby inhibit the progression of alveolar bone resorption.
Journal of periodontology  •  2006  |  View Paper
Individual and combined administration of celecoxib and omega-3 fatty acid significantly increased OC levels compared to the LPS group (P <0.05).
The significantly increased serum OC level observed after individual and combination administration suggests that celecoxib and omega-3 fatty acid may influence bone remodeling and thereby inhibit the progression of alveolar bone resorption.
Journal of periodontology  •  2006  |  View Paper
CONCLUSIONS The results … indicate that celecoxib … omega-3 fatty acid , when used individually, show a rather partial effect on the control of the analyzed mediators, but when combined they show … provide significant reductions in the gingival tissue levels of PGE2, PGF2alpha, LTB4, and PAF in LPS-induced experimental periodontitis.
Combined administration of celecoxib and omega-3 fatty acid exhibited significantly lower values than those of the LPS group in all the analyzed membrane phospholipid mediators (P <0.05), which approximated the levels in the saline control group (P>0.05).
Journal of periodontology  •  2005  |  View Paper