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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“According to the rat experiment, VE supplementation changed coagulation factor IX and CD36 expression in HepG2 cells; thus, in vivo data could be partly confirmed with the in vitro model.”
Modulation of hepatic gene expression by alpha-tocopherol in cultured cells and in vivo.“Fasters reduced their retinol (-0.8 + or - 0.6 micromol/l) and alpha-tocopherol levels (-8.0 + or - 6.6 micromol/L) during the CF period, whereas controls increased them (0.3 + or - 0.7 and 0.4 + or - 4.8 micromol/L, respectively, p<0.001).”
“ VE supplementation down-regulated scavenger receptor CD36, coagulation factor IX and 5-alpha-steroid reductase type 1 mRNA levels while hepatic gamma glutamyl-cysteinyl synthetase was significantly up-regulated.”
Identification of hepatic molecular mechanisms of action of alpha-tocopherol using global gene expression profile analysis in rats.
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