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Discover Supplement-Drug Interactions
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Last Updated: 2 months ago
drug:
Factor Ix
supplement:
Phosphatidylserine
Research Papers that Mention the Interaction
“With tissue factor present, deficiency in factor VIII or IX markedly suppressed thrombus growth, fibrin formation and platelet procoagulant activity ( phosphatidylserine exposure).”
Rate-limiting roles of the tenase complex of factors VIII and IX in platelet procoagulant activity and formation of platelet-fibrin thrombi under flow“With Factor IX alpha , a dependence on the amount of protein bound with the content of PS is seen, which ranges from 338 to 619 molecules/vesicle with membranes containing 30-50% PS.”
The interaction of bovine factor IX, its activation intermediate, factor IX alpha, and its activation products, factor IXa alpha and factor IXa beta, with acidic phospholipid vesicles of various compositions.
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