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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Exenatide
supplement:
Calcium Supplement
Research Papers that Mention the Interaction
“Co-administration of exendin 9-39 with exendin-4 partly … above-mentioned effect of exendin-4.These findings suggest that exendin-4 exerts an antiarrhythmic … decreasing SR calcium leak in spontaneous and burst pacing-induced ventricular arrhythmias, which may … due to reduced RyR2 phosphorylation and suppressed CaMK-II activity.”
“ Exendin-4 reduced calcium spark mass, spark frequency, and calcium leak , which may be due to reduced S2814-RyR2 and CaMK-II phosphorylation.”
Exendin-4 Reduces Ventricular Arrhythmia Activity and Calcium Sparks-Mediated Sarcoplasmic Reticulum Ca Leak in Rats with Heart Failure.“Although this increase in cAMP alone does not result in amylase release, combination of exendin-4 with agents that increase cell calcium results in potentiation of amylase release.”
“ Exendin-4 , when incubated for 24 h, increases CA synthesis by promoting the activation of tyrosine hydroxylase.”
Glucagon-like peptide-1 receptor controls exocytosis in chromaffin cells by increasing full-fusion events.
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